SCHEMBL10020071

SCHEMBL10020071

CCCCCc1ccc(C(=O)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.34
PPARG P37231 2/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
RARB P10826 3/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
TSHR P16473 1/20 0.31
ELANE P08246 3/20 0.31
PRSS1 P07477 1/20 0.31
ACR P10323 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019369 0.96 CTSL (0.34) PPARAPPARGCTSLCTSSCTSK
SCHEMBL19622135 0.92 CTSL (0.32) PPARAPPARGCTSLCTSSCTSK
SCHEMBL19622026 0.91 THRB (0.32) PPARAPPARGCTSLCTSSCTSK
SCHEMBL19621901 0.88 CTSL (0.37) CTSLCTSSCTSK
SCHEMBL10020051 0.88 CTSL (0.37) CTSLCTSSCTSK
SCHEMBL10019896 0.88 PPARA (0.41) PPARAPPARGRARBTHRATHRB
SCHEMBL10020070 0.87 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL19622015 0.87 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10019368 0.86 CTSL (0.37) CTSLCTSSCTSK
SCHEMBL10019691 0.86 PPARA (0.39) PPARAPPARGRARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed