SCHEMBL10020148

SCHEMBL10020148

C=CCCc1ccc(C(F)(F)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020132 0.88 HCRTR1 (0.34) HCRTR1HCRTR2
SCHEMBL10020165 0.88 CTSL (0.31)
SCHEMBL10020178 0.86 HCRTR1 (0.30) HCRTR1HCRTR2
SCHEMBL10019883 0.86 HCRTR1 (0.35) HCRTR1HCRTR2
SCHEMBL10020094 0.86 HCRTR1 (0.33) HCRTR1HCRTR2MEN1ALDH1A1CYP2D6
SCHEMBL10019939 0.86 GAA (0.35) MEN1ALDH1A1CYP2D6KMT2A
SCHEMBL10019966 0.85 FFAR4 (0.36) MEN1ALDH1A1CYP2D6KMT2A
SCHEMBL10019835 0.84 GABRA1 (0.33)
SCHEMBL10020125 0.83
SCHEMBL10019552 0.83 HCRTR1 (0.35) HCRTR1HCRTR2MEN1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed