SCHEMBL10020156

SCHEMBL10020156

CCOc1ccc(COc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.39
NAAA Q02083 1/20 0.38
PKM P14618 2/20 0.37
MAOB P27338 3/20 0.34
FFAR1 O14842 4/20 0.34
PPARD Q03181 4/20 0.34
CSF1R P07333 1/20 0.34
PTGER1 P34995 1/20 0.33
KDM1A O60341 2/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
MTNR1B P49286 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
XBP1 P17861 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020016 0.93 CACNA1C (0.38) CACNA1CNAAAPKMFFAR1PPARD
SCHEMBL10020035 0.90 CACNA1C (0.34) CACNA1CNAAAFFAR1PPARDKDM1A
SCHEMBL10019646 0.89 CACNA1C (0.38) CACNA1CNAAAMAOBFFAR1PPARD
SCHEMBL10019630 0.89 CACNA1C (0.36) CACNA1CNAAAMAOBFFAR1PPARD
SCHEMBL10020030 0.86 CACNA1C (0.39) CACNA1CNAAAMAOBFFAR1PPARD
SCHEMBL10019665 0.86 PKM (0.34) NAAAPKMKDM1AKDM4EMAPT
SCHEMBL10020133 0.86 PKM (0.34) NAAAPKMKDM1AKDM4EMAPT
SCHEMBL10020154 0.85 GABRA1 (0.38) NAAAPKMKDM4ELMNAMAPT
SCHEMBL10019663 0.84 FFAR1 (0.34) CACNA1CNAAAPKMMAOBFFAR1
SCHEMBL10020139 0.82 RXRG (0.39) NAAAFFAR1PPARDKDM1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed