Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70233 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL16950448 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL1483525 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3121267 | 0.81 | HSD17B10 (0.52) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL29606243 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11885424 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL12920465 | 0.81 | MAPT (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL1483367 | 0.81 | MAPT (0.59) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14958355 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL5089887 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8901247-B2 | Responsive polymer system and nanohybrid thin films | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-02 | — | — | US | disclosed |
| US-20120038249-A1 | NOVEL RESPONSIVE POLYMER SYSTEM AND NANOHYBRID THIN FILMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-02-16 | — | — | US | disclosed |