SCHEMBL10020841

SCHEMBL10020841

FC(F)(F)c1cccc(N2COc3ccc(C(c4ccc5c(c4)CN(c4cccc(C(F)(F)F)c4)CO5)(C(F)(F)F)C(F)(F)F)cc3C2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
SIGMAR1 Q99720 2/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR1D P28221 1/20 0.43
HTR2C P28335 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
MAPT P10636 3/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.37
KMT2A Q03164 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020849 0.93 ALDH1A1 (0.47) ALDH1A1CSNK2A2CSNK2BCSNK2A1SIGMAR1
SCHEMBL803060 0.88 ALDH1A1 (0.53) ALDH1A1CSNK2A2CSNK2BCSNK2A1SIGMAR1
SCHEMBL9924580 0.87 ALDH1A1 (0.38) ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL18533345 0.87 ALDH1A1 (0.35) ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL30869946 0.87 ALDH1A1 (0.38) ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL18950006 0.84 VDR (0.50) ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL13578577 0.82 ALDH1A1 (0.37) ALDH1A1CSNK2A2CSNK2BCSNK2A1SIGMAR1
SCHEMBL19107744 0.82 SMN1; SMN2 (0.36) ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT
SCHEMBL17011368 0.80 MAPT (0.32) MAPTLMNASMN1; SMN2KDM4E
SCHEMBL19107741 0.80 GAA (0.38) MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119307-B2 Electrode for fuel cell, method of manufacturing the electrode, and fuel cell employing the electrode SAMSUNG SDI CO., LTD. (KR) 2012-02-21 US disclosed
US-8119307-B2 Electrode for fuel cell, method of manufacturing the electrode, and fuel cell employing the electrode SAMSUNG SDI CO., LTD. (KR) 2012-02-21 US disclosed
US-20080145743-A1 ELECTRODE FOR FUEL CELL, METHOD OF MANUFACTURING THE ELECTRODE, AND FUEL CELL EMPLOYING THE ELECTRODE SAMSUNG SDI CO., LTD. (KR) 2008-06-19 US disclosed
US-20080145743-A1 ELECTRODE FOR FUEL CELL, METHOD OF MANUFACTURING THE ELECTRODE, AND FUEL CELL EMPLOYING THE ELECTRODE SAMSUNG SDI CO., LTD. (KR) 2008-06-19 US disclosed