Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15173149 | 0.87 | KDM4E (0.56) | KDM4ETGFBR1SMN1; SMN2MAPTPOLB | |
| SCHEMBL6259 | 0.85 | TGFBR1 (0.60) | KDM4ETGFBR1NPC1SMN1; SMN2MAPT | |
| SCHEMBL30772298 | 0.85 | TGFBR1 (0.60) | KDM4ETGFBR1NPC1SMN1; SMN2MAPT | |
| SCHEMBL6706707 | 0.82 | KDM4E (0.59) | KDM4ETGFBR1SMN1; SMN2ALOX15HTT | |
| SCHEMBL29766680 | 0.82 | KDM4E (0.59) | KDM4ETGFBR1SMN1; SMN2ALOX15HTT | |
| SCHEMBL15290482 | 0.81 | KDM4E (0.68) | KDM4ETGFBR1NPC1SMN1; SMN2ALOX15 | |
| SCHEMBL10052084 | 0.80 | KDM4E (0.50) | KDM4ENPC1SMN1; SMN2KMT2AADORA3 | |
| SCHEMBL31039975 | 0.80 | TGFBR1 (0.56) | KDM4ETGFBR1NPC1SMN1; SMN2MAPT | |
| SCHEMBL13311187 | 0.80 | CCR1 (0.64) | KDM4ENPC1SMN1; SMN2MAPTPOLB | |
| SCHEMBL29660049 | 0.80 | CCR1 (0.64) | KDM4ENPC1SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546050-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546050-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120052423-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |