SCHEMBL10021050

SCHEMBL10021050

c1ccc(-c2cccc(-c3ccc(-c4c5ccccc5c5c6c(cccc46)-c4c(-c6ccccc6)ccc(-c6ccccc6)c4-5)cc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
ENPP1 P22413 3/20 0.37
ASIC3 Q9UHC3 1/20 0.37
HPGD P15428 3/20 0.35
MAPT P10636 3/20 0.35
POLB P06746 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ACACA Q13085 1/20 0.34
ENPP3 O14638 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
PPARG P37231 2/20 0.33
NR2E3 Q9Y5X4 2/20 0.33
NCOR2 Q9Y618 2/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021054 0.82 KDM4E (0.38) RAB9AHPGDMAPTPOLBALDH1A1
SCHEMBL11992108 0.81 MEN1 (0.47) KMT2AMEN1RAB9AENPP1ASIC3
SCHEMBL17754136 0.77 MEN1 (0.53) KMT2AMEN1RAB9AENPP1ASIC3
SCHEMBL12436890 0.76 MEN1 (0.61) KMT2AMEN1RAB9AASIC3HPGD
SCHEMBL12435997 0.76 MEN1 (0.67) KMT2AMEN1RAB9AENPP1ASIC3
SCHEMBL11992306 0.75 LMNA (0.45) KMT2AMEN1RAB9AENPP1HPGD
SCHEMBL11992109 0.75 CYP1A1 (0.43) KMT2AMEN1RAB9AENPP1HPGD
SCHEMBL11992086 0.75 LMNA (0.45) KMT2AMEN1RAB9AENPP1HPGD
SCHEMBL11992222 0.75 RAB9A (0.40) KMT2AMEN1RAB9AENPP1ASIC3
SCHEMBL10300921 0.75 MEN1 (0.50) KMT2AMEN1RAB9AENPP1ASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110824-B2 Benzo[a]fluoranthene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-8110824-B2 Benzo[a]fluoranthene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-20110049479-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed
US-20110049479-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110049479-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME AFF1, CYP1A1, CYP1B1 KMT2A 1334/4885MEN1 462/4885RAB9A 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.