Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 1.00 |
| ▸ | FAP | Q12884 | 17/20 | 1.00 |
| ▸ | PREP | P48147 | 7/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130472 | 1.00 | DPP4 (1.00) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL15386540 | 0.83 | FAP (0.69) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL13263677 | 0.81 | FAP (0.69) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL12372017 | 0.81 | FAP (0.69) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL13285642 | 0.81 | DPP4 (0.66) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL8288252 | 0.78 | DPP4 (0.65) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL15024904 | 0.78 | DPP4 (0.64) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL12340751 | 0.78 | DPP4 (1.00) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL8286531 | 0.77 | FAP (0.72) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL10022736 | 0.77 | FAP (0.75) | DPP4FAPPREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177582-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2025-06-05 | — | — | US | disclosed |
| CN-118812631-A | Fibroblast activator protein ligand for targeted delivery applications | 菲洛谢姆股份公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115335370-B | Fibroblast activator protein ligand for targeted delivery applications | 菲洛谢姆股份公司 | 2024-08-23 | — | — | CN | disclosed |
| EP-4412996-A1 | RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS | Philochem AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| US-20240216551-A1 | RADIOPHARMACEUTICALS BASED ON ((R)-1-((6-HYDRAZINYLNICOTINOYL)-D-ALANYL)PYRROLIDIN-2-YL)BORONIC ACID (HYNIC-IFAP) FOR DETECTING THE OVEREXPRESSION OF FIBROBLAST ACTIVATION PROTEIN | INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES (MX) | 2024-07-04 | — | — | US | disclosed |
| CN-118234720-A | Radiolabeled fibroblast activation protein ligand | 菲罗化学股份公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4331624-A1 | RADIOPHARMACEUTICALS BASED ON ((R)-1-((6-HYDRAZINYLNICOTINOYL)-D-ALANYL)PYRROLIDIN-2-YL)BORONIC ACID (HYNIC-IFAP) FOR DETECTING THE OVEREXPRESSION OF FIBROBLAST ACTIVATION PROTEIN | Instituto Nacional de Investigaciones Nucleares (MX) | 2024-03-06 | — | — | EP | disclosed |
| CN-117642188-A | Radiopharmaceuticals based on ((R) -1- ((6-hydrazinonicotinyl) -D-alanyl) pyrrolidin-2-yl) boronic acid (HYNIC-IFAP) for detection of fibroblast activation protein overexpression | 国家核研究所 | 2024-03-01 | — | — | CN | disclosed |
| EP-4291554-A1 | BIVALENT FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | Philochem AG (CH) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023144379-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-8268880-B2 | Soft protease inhibitors and pro-soft forms thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268880-B2 | Soft protease inhibitors and pro-soft forms thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120077779-A1 | Inhibitors of Fibroblast Activation Protein Alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077779-A1 | Inhibitors of Fibroblast Activation Protein Alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2012-03-29 | — | — | US | disclosed |
| US-7998997-B2 | Inhibitors of fibroblast activation protein alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2011-08-16 | — | — | US | disclosed |
| US-7998997-B2 | Inhibitors of fibroblast activation protein alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2011-08-16 | — | — | US | disclosed |
| US-20090221818-A1 | Inhibitors of Fibroblast Activation Protein Alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221818-A1 | Inhibitors of Fibroblast Activation Protein Alpha | TRUSTEES OF TUFTS COLLEGE (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090124559-A1 | Soft Protease Inhibitors and Pro-Soft Forms Thereof | TRUSTEES OF TUFTS COLLEGE OFFICE OF TECHNOLOGY AND INDUSTRY COLLABORATION (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090124559-A1 | Soft Protease Inhibitors and Pro-Soft Forms Thereof | TRUSTEES OF TUFTS COLLEGE OFFICE OF TECHNOLOGY AND INDUSTRY COLLABORATION (US) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216551-A1 | RADIOPHARMACEUTICALS BASED ON ((R)-1-((6-HYDRAZINYLNICOTINOYL)-D-ALANYL)PYRROLIDIN-2-YL)BORONIC ACID (HYNIC-IFAP) FOR DETECTING THE OVEREXPRESSION OF FIBROBLAST ACTIVATION PROTEIN | FAP, FIBP, ENPEP | DPP4 569/4885FAP 1/4885PREP 88/4885 |
| US-20120077779-A1 | Inhibitors of Fibroblast Activation Protein Alpha | FIBP, FAP, BCAP31 | DPP4 2154/4885FAP 2/4885PREP 175/4885 |
| US-20090124559-A1 | Soft Protease Inhibitors and Pro-Soft Forms Thereof | PREP, DPP4, PEPD | DPP4 2/4885FAP 51/4885PREP 1/4885 |
| US-20090221818-A1 | Inhibitors of Fibroblast Activation Protein Alpha | FIBP, FAP, BCAP31 | DPP4 2154/4885FAP 2/4885PREP 175/4885 |
| US-20250177582-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | FAP, FIBP, FGFR1 | DPP4 1391/4885FAP 1/4885PREP 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.