Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.50 |
| ▸ | DPP4 | P27487 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022911 | 1.00 | ANPEP (0.50) | ANPEPDPP4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10022913 | 0.79 | ANPEP (0.51) | ANPEPDPP4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2519233 | 0.78 | ANPEP (0.57) | ANPEPDPP4KMT2AGAANR1H2 | |
| SCHEMBL2481189 | 0.76 | DPP4 (0.80) | ANPEPDPP4NR1H2NR1H3 | |
| SCHEMBL2477491 | 0.74 | ANPEP (0.61) | ANPEPDPP4KMT2ASMN1; SMN2NR1H2 | |
| SCHEMBL2477514 | 0.72 | ANPEP (0.58) | ANPEPDPP4KMT2ASMN1; SMN2NR1H2 | |
| SCHEMBL2989683 | 0.72 | ANPEP (0.55) | ANPEPDPP4KMT2AGAANR1H2 | |
| SCHEMBL2479315 | 0.71 | ANPEP (0.57) | ANPEPDPP4KMT2ANR1H2NR1H3 | |
| SCHEMBL4864907 | 0.71 | ANPEP (0.54) | ANPEPDPP4KMT2AALDH1A1NR1H2 | |
| SCHEMBL2476501 | 0.70 | ANPEP (0.59) | ANPEPDPP4KMT2ASMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085608-A2 | USE OF TRIFLUORO PHTHALIMIDES FOR THE TREATMENT OF CANCEROUS DISEASES | "AVIDIN" KUTATÓ, FEJLESZTÖ ÉS KERESKEDELMI KORLÁTOLT (HU) | 2012-06-28 | — | — | WO | disclosed |