Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.59 |
| ▸ | DPP4 | P27487 | 6/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477491 | 0.94 | ANPEP (0.61) | ANPEPDPP4NR1H2NR1H3MEN1 | |
| SCHEMBL2477212 | 0.86 | ANPEP (0.55) | ANPEPDPP4NR1H2NR1H3 | |
| SCHEMBL2480594 | 0.86 | ANPEP (0.55) | ANPEPDPP4NR1H2NR1H3MEN1 | |
| SCHEMBL2481189 | 0.83 | DPP4 (0.80) | ANPEPDPP4NR1H2NR1H3LMNA | |
| SCHEMBL2477514 | 0.81 | ANPEP (0.58) | ANPEPDPP4NR1H2NR1H3MEN1 | |
| SCHEMBL11910731 | 0.81 | ANPEP (0.49) | ANPEPDPP4MEN1KMT2AMAPT | |
| SCHEMBL2479315 | 0.81 | ANPEP (0.57) | ANPEPDPP4NR1H2NR1H3MEN1 | |
| SCHEMBL2989683 | 0.79 | ANPEP (0.55) | ANPEPDPP4NR1H2NR1H3MEN1 | |
| SCHEMBL17531038 | 0.79 | DPP4 (0.68) | ANPEPDPP4NR1H2NR1H3LMNA | |
| SCHEMBL11888788 | 0.78 | ANPEP (0.46) | ANPEPDPP4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | claimed |
| EP-2373618-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | Avidin KFT (HU) | 2011-10-12 | — | — | EP | claimed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | claimed |
| WO-2008155593-A2 | PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES | AVICOR KUTATO (HU) | 2008-12-24 | — | — | WO | claimed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | claimed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| EP-2373618-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | Avidin KFT (HU) | 2011-10-12 | — | — | EP | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| WO-2008155593-A2 | PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES | AVICOR KUTATO (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155593-A2 | PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES | AVICOR KUTATO (HU) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | NSFL1C, LIPC, NPC1L1 | ANPEP 4444/4885DPP4 3452/4885NR1H2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.