Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.80 |
| ▸ | ANPEP | P15144 | 5/20 | 0.80 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531038 | 0.92 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL4790200 | 0.91 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL4789525 | 0.89 | DPP4 (0.66) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL12748799 | 0.87 | DPP4 (0.63) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL2477491 | 0.85 | ANPEP (0.61) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL2476501 | 0.83 | ANPEP (0.59) | DPP4ANPEPNR1H2NR1H3FAAH | |
| SCHEMBL2477514 | 0.83 | ANPEP (0.58) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL2496662 | 0.83 | ANPEP (0.58) | DPP4ANPEPNR1H2NR1H3CA1 | |
| SCHEMBL2519233 | 0.82 | ANPEP (0.57) | DPP4ANPEPNR1H2NR1H3PTGS1 | |
| SCHEMBL2479315 | 0.82 | ANPEP (0.57) | DPP4ANPEPNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746191-B2 | Polymers for selective heavy metal removal | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-05 | — | — | US | claimed |
| WO-2019023215-A1 | POLYMERS FOR SELECTIVE HEAVY METAL REMOVAL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-31 | — | — | WO | claimed |
| US-20190031832-A1 | Polymers for Selective Heavy Metal Removal | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-01-31 | — | — | US | claimed |
| JP-10072346-A | — | — | None | — | — | JP | disclosed |
| US-11746191-B2 | Polymers for selective heavy metal removal | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-05 | — | — | US | disclosed |
| US-20190031832-A1 | Polymers for Selective Heavy Metal Removal | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-01-31 | — | — | US | disclosed |
| WO-2019023215-A1 | POLYMERS FOR SELECTIVE HEAVY METAL REMOVAL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-31 | — | — | WO | disclosed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| US-8232299-B2 | Phthalimide derivatives that influence cellular vesicular systems, pharmaceutical compositions, and use thereof | AVIDIN KFT. (HU) | 2012-07-31 | — | — | US | disclosed |
| EP-2373618-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | Avidin KFT (HU) | 2011-10-12 | — | — | EP | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2010-07-22 | — | — | US | disclosed |
| WO-2008155593-A2 | PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES | AVICOR KUTATO (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155594-A2 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | AVIDIN KFT (HU) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155593-A2 | PHTHALIMIDE DERIVATIVES FOR LABELING LIPID DROPLETS, AND A METHOD FOR VISUALIZATION OF CELLS AND/OR CELLULAR ORGANELLES | AVICOR KUTATO (HU) | 2008-12-24 | — | — | WO | disclosed |
| JP-H1072346-A | TUMOR NECROSIS FACTOR PRODUCTION-INHIBITING MEDICINE OR VASCULARIZATION-INHIBITING MEDICINE CONTAINING N-PHENYLPHTHALIMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1998-03-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184762-A1 | PHTHALIMIDE DERIVATIVES THAT INFLUENCE CELLULAR VESICULAR SYSTEMS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF | NSFL1C, LIPC, NPC1L1 | DPP4 3452/4885ANPEP 4444/4885NR1H2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.