Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 8/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48681 | 0.90 | MEN1 (0.58) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL30115197 | 0.90 | MEN1 (0.58) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL30115198 | 0.90 | MEN1 (0.58) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL48847 | 0.89 | MEN1 (0.57) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL8444747 | 0.89 | MEN1 (0.57) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL49291 | 0.89 | PIM1 (0.59) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL31384188 | 0.89 | PIM1 (0.59) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL3774114 | 0.87 | PIM1 (0.58) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL4385090 | 0.82 | MEN1 (0.53) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL9102418 | 0.79 | MAPT (0.53) | MEN1KMT2ALMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124443-B2 | Organic diodes and materials | MARROCCO MATTHEW L (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100112751-A1 | ORGANIC DIODES AND MATERIALS | MARROCCO III MATTHEW L | 2010-05-06 | — | — | US | disclosed |
| US-7655961-B2 | Organic diodes and materials | MAXDEM INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |