SCHEMBL49291

SCHEMBL49291

O=S(=O)(O)CCCCN1c2ccccc2Sc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.59
KDM1A O60341 9/20 0.55
MAPT P10636 4/20 0.55
ALOX15 P16050 3/20 0.55
TP53 P04637 2/20 0.55
KDM4E B2RXH2 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
USP2 O75604 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
RAD52 P43351 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
LMNA P02545 3/20 0.54
MMP13 P45452 2/20 0.54
POLB P06746 2/20 0.54
SIGMAR1 Q99720 2/20 0.53
SLC22A1 O15245 1/20 0.53
PRNP P04156 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31384188 1.00 PIM1 (0.59) PIM1KDM1AMAPTALOX15TP53
SCHEMBL3774114 0.98 PIM1 (0.58) PIM1KDM1AMAPTALOX15TP53
SCHEMBL30115198 0.95 MEN1 (0.58) PIM1KDM1AMAPTALOX15TP53
SCHEMBL30115197 0.95 MEN1 (0.58) PIM1KDM1AMAPTALOX15TP53
SCHEMBL48681 0.95 MEN1 (0.58) PIM1KDM1AMAPTALOX15TP53
SCHEMBL8444747 0.94 MEN1 (0.57) PIM1KDM1AMAPTALOX15TP53
SCHEMBL48847 0.94 MEN1 (0.57) PIM1KDM1AMAPTALOX15TP53
SCHEMBL10023985 0.89 MEN1 (0.58) PIM1KDM1AMAPTALOX15TP53
SCHEMBL22024566 0.88 MAPT (0.72) KDM1AMAPTALOX15TP53KDM4E
SCHEMBL9102304 0.84 MAPT (0.64) KDM1AMAPTALOX15TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230417755-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S R L (IT) 2023-12-28 US claimed
EP-3686285-B1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S R L (IT) 2023-10-11 EP claimed
US-11761964-B2 Ultra-sensitive chemiluminescent substrates for peroxidase CYANAGEN S.R.L. (IT) 2023-09-19 US claimed
EP-3686285-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE Cyanagen S.r.l. (IT) 2020-07-29 EP claimed
CN-111454718-A Ultrasensitive chemiluminescent substrates for peroxidases 喜雅纳肯有限公司 2020-07-28 CN claimed
US-20200232991-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S.R.L. (IT) 2020-07-23 US claimed
EP-1950207-B1 Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity CYANAGEN SRL (IT) 2012-06-20 EP claimed
US-7855287-B2 Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity CYANAGEN SRL (IT) 2010-12-21 US claimed
EP-1950207-A1 Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity Cyanagen Srl (IT) 2008-07-30 EP claimed
US-20080176251-A1 Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase acitivity CYANAGEN SRL (IT) 2008-07-24 US claimed
US-20230417755-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S R L (IT) 2023-12-28 US disclosed
EP-3686285-B1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S R L (IT) 2023-10-11 EP disclosed
US-11761964-B2 Ultra-sensitive chemiluminescent substrates for peroxidase CYANAGEN S.R.L. (IT) 2023-09-19 US disclosed
US-11268955-B2 Use of absorbent particles to improve signal detection in an analysis method BIO-RAD EUROPE GMBH (CH) 2022-03-08 US disclosed
US-11112366-B2 Reagent and kit for enhancing chemiluminescent reaction NATIONAL TAIWAN OCEAN UNIVERSITY (TW) 2021-09-07 US disclosed
US-7803573-B2 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2010-09-28 US disclosed
US-7709547-B2 Ink composition, inkjet recording method, printed material, production method of a planographic printing plate and planographic printing plate FUJIFILM CORPORATION (JP) 2010-05-04 US disclosed
US-20080241868-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2008-10-02 US disclosed
EP-1962095-A1 Method for increasing light emission from a chemiluminescent reaction Cyanagen Srl (IT) 2008-08-27 EP disclosed
US-20070115326-A1 Ink composition, inkjet recording method, printed material, production method of a planographic printing plate and planographic printing plate FUJIFILM CORPORATION 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11112366-B2 Reagent and kit for enhancing chemiluminescent reaction MPO, LPO, KIT PIM1 682/4885KDM1A 1277/4885MAPT 4804/4885
US-20080176251-A1 Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase acitivity LPO, ARSA, SULT1E1 PIM1 1020/4885KDM1A 2334/4885MAPT 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.