Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.88 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21367403 | 0.94 | TERT (1.00) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6233141 | 0.92 | TERT (0.97) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6234517 | 0.91 | TERT (0.94) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL34460910 | 0.88 | TERT (0.82) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL10062486 | 0.85 | TERT (0.61) | TERTSTAT3HIF1ACYP1B1KDM4E | |
| SCHEMBL6234260 | 0.84 | TERT (0.87) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL34460906 | 0.84 | TERT (0.87) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| SCHEMBL19101461 | 0.84 | TERT (0.61) | TERTSTAT3HIF1ACYP1B1KDM4E | |
| SCHEMBL16558634 | 0.84 | TERT (0.86) | TERTSTAT3HIF1AKDM4EALDH1A1 | |
| Iodide SCHEMBL6230746 | 0.83 | TERT (0.84) | TERTSTAT3HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124443-B2 | Organic diodes and materials | MARROCCO MATTHEW L (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124443-B2 | Organic diodes and materials | MARROCCO MATTHEW L (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100112751-A1 | ORGANIC DIODES AND MATERIALS | MARROCCO III MATTHEW L | 2010-05-06 | — | — | US | disclosed |
| US-20100112751-A1 | ORGANIC DIODES AND MATERIALS | MARROCCO III MATTHEW L | 2010-05-06 | — | — | US | disclosed |
| US-7655961-B2 | Organic diodes and materials | MAXDEM INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655961-B2 | Organic diodes and materials | MAXDEM INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |