Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024564 | 0.86 | — | — | |
| SCHEMBL10024565 | 0.82 | — | — | |
| SCHEMBL12313929 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL10024566 | 0.74 | TSHR (0.31) | BBOX1 | |
| SCHEMBL1970826 | 0.72 | BBOX1 (0.55) | BBOX1MEN1LMNAPOLBGRK2 | |
| SCHEMBL23534197 | 0.71 | BBOX1 (0.58) | BBOX1MEN1LMNAPOLBGRK2 | |
| SCHEMBL1244413 | 0.71 | BBOX1 (0.53) | BBOX1LMNA | |
| SCHEMBL20199370 | 0.70 | BBOX1 (0.60) | BBOX1MEN1LMNAPOLBGRK2 | |
| SCHEMBL22264065 | 0.68 | LMNA (0.57) | BBOX1LMNA | |
| SCHEMBL25663649 | 0.67 | BBOX1 (0.73) | BBOX1MEN1LMNAPOLBGRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237670-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2237673-B1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-8470894-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS (US) | 2013-06-25 | — | — | US | disclosed |
| US-8263669-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120142535-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2012-06-07 | — | — | US | disclosed |
| US-20110028569-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-02-03 | — | — | US | disclosed |
| US-20110021644-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-27 | — | — | US | disclosed |
| EP-2237670-A2 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| EP-2237673-A2 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| US-20090173912-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20090176893-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| WO-2009085300-A2 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085297-A2 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028569-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM1, CHRM2, CD209 | BBOX1 3760/4885MEN1 2412/4885LMNA 3024/4885 |
| US-20090176893-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM2, CHRM1, MSR1 | BBOX1 1416/4885MEN1 1090/4885LMNA 2806/4885 |
| US-20120142535-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM2, CHRM1, MSR1 | BBOX1 1733/4885MEN1 1202/4885LMNA 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.