SCHEMBL10024973

SCHEMBL10024973

CCCC(C)(C)N1Cc2ccc(C(=O)Nc3ccc(Oc4ccc(C(C)(CC)CC)cc4)cc3)cc2C1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 18/20 0.45
L3MBTL3 Q96JM7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10025008 0.93 NAMPT (0.45) NAMPTL3MBTL3
SCHEMBL10025010 0.79 NAMPT (0.47) NAMPTL3MBTL3
SCHEMBL10024974 0.74 SMN1; SMN2 (0.49) NAMPTL3MBTL3
SCHEMBL13930992 0.72 RAB9A (0.71)
SCHEMBL10000285 0.71 RAB9A (0.52) NAMPT
SCHEMBL9695836 0.68 SNCA (0.54)
SCHEMBL19339482 0.66 ELANE (0.49)
SCHEMBL25757213 0.66 HDAC3 (0.51) NAMPT
SCHEMBL21658208 0.66 MAPK1 (0.45)
SCHEMBL12588318 0.65 MAPK1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101009-B2 Separation membrane by controlled annealing of polyimide polymers L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2012-01-24 US disclosed
US-20090227744-A1 Separation Membrane by Controlled Annealing of Polyimide Polymers L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2009-09-10 US disclosed