Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025010 | 0.85 | NAMPT (0.47) | ALDH1A1NAMPTL3MBTL3 | |
| SCHEMBL10025008 | 0.80 | NAMPT (0.45) | NPC1TP53NAMPTL3MBTL3 | |
| SCHEMBL20873124 | 0.75 | LMNA (0.52) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL10024973 | 0.74 | NAMPT (0.45) | NAMPTL3MBTL3 | |
| SCHEMBL23844169 | 0.72 | LMNA (0.76) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL9978816 | 0.70 | RAB9A (0.67) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL7296425 | 0.70 | NR1H4 (0.76) | SMN1; SMN2NPC1RAB9ALMNAKDM4E | |
| SCHEMBL12895849 | 0.69 | RAB9A (0.69) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL17660210 | 0.69 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL10000286 | 0.68 | RAB9A (0.59) | SMN1; SMN2NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101009-B2 | Separation membrane by controlled annealing of polyimide polymers | L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2012-01-24 | — | — | US | disclosed |
| US-20090227744-A1 | Separation Membrane by Controlled Annealing of Polyimide Polymers | L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2009-09-10 | — | — | US | disclosed |