Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | GRM5 | P41594 | 11/20 | 0.79 |
| ▸ | MAOB | P27338 | 6/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.76 |
| ▸ | STAT1 | P42224 | 1/20 | 0.74 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955465 | 0.89 | RAB9A (0.80) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL10025793 | 0.87 | GRM5 (0.80) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9956150 | 0.87 | GRM5 (1.00) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9955087 | 0.87 | GRM5 (0.80) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL10025797 | 0.87 | RAB9A (1.00) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9955883 | 0.86 | RAB9A (0.78) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9956161 | 0.86 | GRM5 (1.00) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL10025794 | 0.85 | RAB9A (1.00) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9956481 | 0.85 | GRM5 (0.76) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL9955979 | 0.84 | GRM5 (0.76) | RAB9AALDH1A1NPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481459-B2 | Chemical inhibitors of ethylene biosynthesis | ACADEMIA SINICA (TW) | 2013-07-09 | — | — | US | disclosed |
| US-8481459-B2 | Chemical inhibitors of ethylene biosynthesis | ACADEMIA SINICA (TW) | 2013-07-09 | — | — | US | disclosed |
| US-20120023625-A1 | CHEMICAL INHIBITORS OF ETHYLENE BIOSYNTHESIS | ACADEMIA SINICA (TW) | 2012-01-26 | — | — | US | disclosed |
| US-20120023625-A1 | CHEMICAL INHIBITORS OF ETHYLENE BIOSYNTHESIS | ACADEMIA SINICA (TW) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120023625-A1 | CHEMICAL INHIBITORS OF ETHYLENE BIOSYNTHESIS | COASY, ACACB, FDPS | RAB9A 3997/4885ALDH1A1 535/4885NPC1 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.