Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 6/20 | 0.41 |
| ▸ | CCR8 | P51685 | 6/20 | 0.41 |
| ▸ | CCR5 | P51681 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863911 | 0.89 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL713323 | 0.89 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL21298469 | 0.88 | L3MBTL1 (0.43) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL15251334 | 0.87 | L3MBTL1 (0.50) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL29489795 | 0.87 | L3MBTL1 (0.50) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL21791178 | 0.85 | HPRT1 (0.44) | L3MBTL1HSP90AA1NPC1CCR1CCR8 | |
| SCHEMBL18816320 | 0.84 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1NPC1MEN1KMT2A | |
| SCHEMBL31607191 | 0.83 | HPRT1 (0.48) | L3MBTL1HSP90AA1NPC1CCR1CCR8 | |
| SCHEMBL21297912 | 0.83 | HPRT1 (0.48) | L3MBTL1HSP90AA1NPC1CCR1CCR8 | |
| SCHEMBL21298467 | 0.82 | HSP90AA1 (0.41) | L3MBTL1HSP90AA1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | L3MBTL1 1759/4885HSP90AA1 4475/4885NPC1 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.