Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612448 | 0.78 | ALDH1A1 (0.34) | CYP3A4 | |
| SCHEMBL27817285 | 0.71 | APP (0.39) | APP | |
| SCHEMBL5498507 | 0.64 | ALDH1A1 (0.47) | — | |
| SCHEMBL1932991 | 0.62 | CYP3A4 (0.42) | APPCYP3A4IDO1 | |
| SCHEMBL2099516 | 0.62 | APP (0.48) | APP | |
| SCHEMBL12893293 | 0.61 | ALDH1A1 (0.54) | APP | |
| SCHEMBL6477818 | 0.61 | TPMT (0.39) | APP | |
| SCHEMBL12893268 | 0.61 | ALDH1A1 (0.54) | APP | |
| SCHEMBL7068355 | 0.61 | CHKA (0.43) | APP | |
| SCHEMBL985323 | 0.60 | APP (0.44) | APPCYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015241-A1 | SUBSTITUTED HETEROCYCLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015241-A1 | SUBSTITUTED HETEROCYCLES AND USE THEREOF | F2, VKORC1, HMBS | APP 2059/4885CYP3A4 39/4885IDO1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.