Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17249781 | 0.91 | PDK2 (0.37) | PDK2PGR | |
| SCHEMBL10027688 | 0.90 | PDK2 (0.40) | PDK2PGRMEN1NPC1RAB9A | |
| SCHEMBL266549 | 0.89 | MEN1 (0.34) | PDK2PGRMEN1KMT2A | |
| SCHEMBL25445471 | 0.85 | PDK2 (0.38) | PDK2PGRMEN1NPC1RAB9A | |
| SCHEMBL25445490 | 0.85 | PDK2 (0.33) | PDK2PGR | |
| SCHEMBL20345612 | 0.85 | PDK2 (0.42) | PDK2PGR | |
| SCHEMBL22241048 | 0.82 | PDK2 (0.43) | PDK2PGRMEN1KMT2A | |
| SCHEMBL25445887 | 0.81 | PDK2 (0.40) | PDK2 | |
| SCHEMBL18759122 | 0.81 | KDM4E (0.30) | — | |
| SCHEMBL14850147 | 0.80 | PGR (0.34) | PDK2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835113-B2 | Methods and compositions for assaying a sample for an aggregant | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140087480-A1 | Methods and Compositions for Assaying a Sample for an Aggregant | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-27 | — | — | US | disclosed |
| US-8546081-B2 | Methods and compositions for assaying a sample for an aggregant | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120214255-A1 | METHODS AND COMPOSITIONS FOR ASSAYING A SAMPLE FOR AN AGGREGANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-23 | — | — | US | disclosed |
| US-8110673-B2 | Aggregation sensor and solutions and kits comprising the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100255477-A1 | METHODS AND COMPOSITIONS FOR ASSAYING A SAMPLE FOR AN AGGREGANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-07 | — | — | US | disclosed |
| US-7666594-B2 | biosensors; cationic polymers; peptide nucleic acids; point mutations; quantitative analysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-23 | — | — | US | disclosed |