Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266549 | 0.90 | MEN1 (0.34) | PDK2LMNAPGRMEN1MAPT | |
| SCHEMBL10027687 | 0.90 | PDK2 (0.40) | PDK2PGRMEN1KMT2ANPC1 | |
| SCHEMBL17249781 | 0.85 | PDK2 (0.37) | PDK2PGR | |
| SCHEMBL13958188 | 0.84 | LMNA (0.42) | LMNAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL25445501 | 0.82 | MCL1 (0.35) | PDK2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20345612 | 0.82 | PDK2 (0.42) | PDK2PGR | |
| SCHEMBL20806202 | 0.79 | COMT (0.39) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL22241048 | 0.78 | PDK2 (0.43) | PDK2PGRMEN1KMT2AKDM4E | |
| SCHEMBL15975348 | 0.78 | PDK2 (0.34) | PDK2 | |
| SCHEMBL25445887 | 0.77 | PDK2 (0.40) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546081-B2 | Methods and compositions for assaying a sample for an aggregant | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120214255-A1 | METHODS AND COMPOSITIONS FOR ASSAYING A SAMPLE FOR AN AGGREGANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-23 | — | — | US | disclosed |
| US-8110673-B2 | Aggregation sensor and solutions and kits comprising the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100255477-A1 | METHODS AND COMPOSITIONS FOR ASSAYING A SAMPLE FOR AN AGGREGANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-07 | — | — | US | disclosed |
| US-7666594-B2 | biosensors; cationic polymers; peptide nucleic acids; point mutations; quantitative analysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-23 | — | — | US | disclosed |