Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013406 | 0.95 | HDAC6 (0.55) | NAMPTGAAHPGDCYP1A2TSHR | |
| SCHEMBL7517981 | 0.93 | HDAC6 (0.57) | NAMPTGAAHPGDHDAC6HDAC1 | |
| SCHEMBL5178440 | 0.93 | HDAC6 (0.57) | NAMPTGAAHPGDHDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL524680 | 0.91 | HDAC6 (0.56) | NAMPTGAAHPGDHDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL7557310 | 0.91 | HDAC6 (0.56) | NAMPTGAAHPGDHDAC6HDAC1 | |
| SCHEMBL1006489 | 0.89 | NAMPT (0.54) | NAMPTGAAHPGDHDAC6HDAC1 | |
| SCHEMBL11210960 | 0.89 | HDAC6 (0.59) | HDAC6HDAC1CDK4CCND1MEN1 | |
| SCHEMBL8641718 | 0.89 | HDAC6 (0.59) | HDAC6HDAC1CDK4CCND1MEN1 | |
| SCHEMBL11210779 | 0.86 | KMT2A (0.56) | HPGDHDAC6HDAC1ALDH1A1CDK4 | |
| SCHEMBL16151551 | 0.86 | ACACB (0.51) | NAMPTGAAHPGDCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212261-A | LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS | HENKEL RESEARCH CORPORATION (US) | 1993-05-18 | — | — | US | claimed |
| WO-1992011307-A1 | LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS | HENKEL RESEARCH CORPORATION (US) | 1992-07-09 | — | — | WO | claimed |
| EP-3332645-A1 | USE OF SUBSTITUTED PYRIMIDINE DIONES OR THEIR SALTS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | Bayer Cropscience AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2015116806-A1 | PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS | PROMEGA CORPORATION (US) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015046618-A1 | DYE COMPOUND, INK, AND RESIST COMPOSITION FOR COLOR FILTER | CANON KABUSHIKI KAISHA (JP) | 2015-04-02 | — | — | WO | disclosed |
| US-8816070-B2 | Triazole derivative as an HSP 90 inhibitor | MERCK PATENT GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-8778219-B2 | Ionic liquids for separation of olefin-paraffin mixtures | UT-BATTELLE, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130338389-A1 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | UT-BATTELLE, LLC (US) | 2013-12-19 | — | — | US | disclosed |
| US-8535560-B2 | Ionic liquids for separation of olefin-paraffin mixtures | UT-BATTELLE, LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20110015461-A1 | Ionic Liquids for Separation of Olefin-Paraffin Mixtures | UT-BATTELLE, LLC (US) | 2011-01-20 | — | — | US | disclosed |
| WO-2011008664-A2 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | UT-BATTELLE, LLC (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20100113542-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | MERCK PATENT GESELLSCHAFT (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-1521746-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-Ceptor Therapeutics, Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003076418-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-09-18 | — | — | WO | disclosed |
| US-20020055638-A1 | Process for the preparation of carboxamides by oxidation of aldehydes in the presence of amines | DEGUSSA AG (DE) | 2002-05-09 | — | — | US | disclosed |
| EP-1179525-A1 | Process for the preparation of carboxylic acid amides by oxidation of aldehydes in the presence of amines | Degussa Aktiengesellschaft (DE) | 2002-02-13 | — | — | EP | disclosed |
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | disclosed |
| US-5212261-A | LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS | HENKEL RESEARCH CORPORATION (US) | 1993-05-18 | — | — | US | disclosed |
| WO-1992011307-A1 | LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS | HENKEL RESEARCH CORPORATION (US) | 1992-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338389-A1 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | POU2F1, POU2F2, POF1B | NAMPT 3267/4885GAA 4868/4885HPGD 3260/4885 |
| US-20020055638-A1 | Process for the preparation of carboxamides by oxidation of aldehydes in the presence of amines | CBR1, CBR3, TECR | NAMPT 1341/4885GAA 2587/4885HPGD 2467/4885 |
| US-20100113542-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | HSP90AB1, HSP90AB2P, HSP90AA1 | NAMPT 1529/4885GAA 1163/4885HPGD 959/4885 |
| US-20110015461-A1 | Ionic Liquids for Separation of Olefin-Paraffin Mixtures | POU2F1, POU2F2, POF1B | NAMPT 3267/4885GAA 4868/4885HPGD 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.