SCHEMBL11210779

SCHEMBL11210779

CN(CCN(C)C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
CDK4 P11802 1/20 0.55
CCND1 P24385 1/20 0.55
MLYCD O95822 2/20 0.54
HDAC6 Q9UBN7 2/20 0.53
HDAC1 Q13547 1/20 0.53
ACHE P22303 1/20 0.51
TNF P01375 1/20 0.51
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
HSD11B1 P28845 1/20 0.50
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
MCHR1 Q99705 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6598473 0.94 KMT2A (0.51) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL8641718 0.90 HDAC6 (0.59) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL11210960 0.90 HDAC6 (0.59) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL1006489 0.90 NAMPT (0.54) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL1004454 0.90 KMT2A (0.51) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL13585636 0.89 MLYCD (0.50) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL1003843 0.88 ADRA2C (0.53) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL13460050 0.88 KMT2A (0.52) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL9873675 0.88 MLYCD (0.53) KMT2AMEN1CDK4CCND1MLYCD
SCHEMBL482541 0.88 KMT2A (0.50) KMT2AMEN1CDK4CCND1MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007127-A1 METHOD OF SELECTIVE PRECIPITATION OF METALS USING AMIDE COMPOUNDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2023-02-02 WO disclosed
US-4386053-A IMPREGNATION OF SUBSTRATE WITH ORGANIC PEROXIDE, CHROMOGEN, BUFFER AND STABILIZER TERUMO CORPORATION (JP) 1983-05-31 US disclosed