Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876356 | 0.95 | HTT (0.59) | HTTHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL13955820 | 0.76 | KCNMA1 (0.52) | HTTHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL13213971 | 0.75 | MEN1 (0.57) | HTTHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL10027983 | 0.74 | NPC1 (0.55) | KDM4EALDH1A1HPGDKMT2AGAA | |
| SCHEMBL13213970 | 0.74 | HTT (0.56) | HTTHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL13645904 | 0.74 | MAPK14 (0.45) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL1273833 | 0.74 | GAA (0.70) | HTTHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL13213988 | 0.73 | KMT2A (0.52) | HTTHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL413038 | 0.72 | NPC1 (0.61) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL8410525 | 0.72 | HDAC1 (0.50) | HDAC1HDAC8HDAC6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021357-A1 | POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME | NEC CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |