Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413038 | 0.94 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2POLBAHR | |
| SCHEMBL5031620 | 0.78 | GAA (0.54) | NPC1RAB9ASMN1; SMN2POLBAHR | |
| SCHEMBL14030980 | 0.76 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2POLBAHR | |
| SCHEMBL14031075 | 0.76 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL18100388 | 0.76 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL14030937 | 0.75 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL8970981 | 0.75 | PTK2 (0.70) | NPC1RAB9ASMN1; SMN2AHRMEN1 | |
| SCHEMBL1858961 | 0.75 | GAA (0.51) | NPC1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10027982 | 0.74 | HTT (0.54) | SMN1; SMN2POLBHPGDAHRMEN1 | |
| SCHEMBL5182550 | 0.74 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2POLBAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021357-A1 | POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME | NEC CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |