⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL10390314 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL2873676 | 0.75 | — | — | |
| SCHEMBL13400166 | 0.73 | GAA (0.43) | — | |
| SCHEMBL13156166 | 0.73 | GAA (0.38) | — | |
| SCHEMBL1026014 | 0.73 | — | — | |
| SCHEMBL269270 | 0.71 | — | — | |
| SCHEMBL1691615 | 0.71 | — | — | |
| SCHEMBL12301795 | 0.71 | ACLY (0.38) | — | |
| SCHEMBL21663995 | 0.71 | — | — | |
| SCHEMBL18882997 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314712-B2 | Functionalized substrates with ion-exchange properties | DIONEX CORPORATION (US) | 2016-04-19 | — | — | US | disclosed |
| US-9310344-B2 | HILIC/anion-exchange/cation-exchange multimodal media | DIONEX CORPORATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140370614-A1 | HILIC / ANION-EXCHANGE / CATION-EXCHANGE MULTIMODAL MEDIA | DIONEX CORPORATION | 2014-12-18 | — | — | US | disclosed |
| US-8367065-B2 | Targeted polymeric prodrugs containing multifunctional linkers | ENZON PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8110559-B2 | Hindered ester-based biodegradable linkers for oligonucleotide delivery | ENZON PHARMACEUTICALS, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| US-20110230420-A1 | RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS | ENZON PHARMACEUTICALS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
| US-20100234444-A1 | HINDERED ESTER-BASED BIODEGRADABLE LINKERS FOR OLIGONUCLEOTIDE DELIVERY | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100233190-A1 | TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20090277838-A1 | Functionalized substrates with ion-exchange properties | DIONEX CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090202573-A1 | POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES | ENZON PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20070010689-A1 | Optically active 3,3'-dithiobis(2-amino-2methylpropionic acid) derivative and process for producing optically active 2-amino-3-mercapto-2-methylpropionic acid derivative | KANEKA CORPORATION (JP) | 2007-01-11 | — | — | US | disclosed |