⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626026 | 0.80 | — | — | |
| SCHEMBL8233980 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL3837756 | 0.74 | — | — | |
| SCHEMBL2928353 | 0.74 | — | — | |
| SCHEMBL2928356 | 0.74 | — | — | |
| SCHEMBL2873676 | 0.73 | — | — | |
| SCHEMBL188468 | 0.73 | — | — | |
| SCHEMBL276535 | 0.73 | — | — | |
| SCHEMBL1327762 | 0.73 | — | — | |
| SCHEMBL10028027 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967045-B | Intermediate of heteroacene compound, and synthesis method of heteroacene compound using the same | 三星电子株式会社 | 2021-09-14 | — | — | CN | disclosed |
| EP-3124489-B1 | THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN INC (US) | 2020-07-15 | — | — | EP | disclosed |
| US-10711026-B2 | Spinosyn derivatives as insecticides | AGRIMETIS, LLC (US) | 2020-07-14 | — | — | US | disclosed |
| EP-3344610-B1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20190309007-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2019-10-10 | — | — | US | disclosed |
| CN-108602778-A | 8-amino-2-oxo-1, 3-diaza-spiro- [4.5] -decane derivatives | 格吕伦塔尔有限公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-3344610-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | Agrimetis, LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| CN-108137528-A | Pleocidin derivative as insecticide | 阿格里麦蒂斯有限责任公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107921037-A | The drug regimen of ALPELISIB and B the RAF inhibitor dabrafenibs of inhibitor containing PI3K；Application of the combination in cancer is treated or prevented | 诺华股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-106967045-A | The intermediate of miscellaneous acene compound, the synthetic method using its miscellaneous acene compound and include the electronic device of miscellaneous acene compound | 三星电子株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-102471351-A | 2-carboxamide cyclosemicarbazides as PI3K inhibitors | NOVARTIS AG | 2012-05-23 | — | — | CN | disclosed |
| EP-2448946-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | Novartis AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| CN-101379049-B | Novel benzamidine derivatives, process for preparing the same, and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD | 2012-01-04 | — | — | CN | disclosed |
| WO-2011000855-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |
| US-20110003786-A1 | 2-Carboxamide Cycloamino Ureas | NOVARTIS AG | 2011-01-06 | — | — | US | disclosed |
| US-7696223-B2 | [(2-bromo-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acid; modulates the stability and/or activity of hypoxia inducible factor (HIF) | FIBROGEN, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| EP-2016078-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20080004309-A1 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2008-01-03 | — | — | US | disclosed |
| WO-2007115315-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2007-10-11 | — | — | WO | disclosed |
| US-4742056-A | CONTROLLING INSECTS AND REPRESENTATIVES FOR THE ORDER ACARINA | CIBA-GEIGY CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |