Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.45 |
| ▸ | ESRRA | P11474 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801169 | 0.87 | CHEK1 (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29357116 | 0.87 | CHEK1 (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29758423 | 0.87 | CHEK1 (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL10000631 | 0.85 | HSP90AA1 (0.48) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL23566815 | 0.84 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| Ethylene SCHEMBL6266470 | 0.84 | CHEK1 (0.46) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL4770065 | 0.83 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| Ethylene Glycol SCHEMBL11709595 | 0.83 | CHEK1 (0.44) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| Glycolic Acid SCHEMBL5562280 | 0.83 | CHEK1 (0.44) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| Ethylene Glycol SCHEMBL39427 | 0.83 | CHEK1 (0.44) | ALDH1A1ALOX15HSD17B10NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093320-B2 | Compositions comprising polyphosphonates and additives that exhibit an advantageous combination of properties, and methods related thereto | FRX POLYMERS, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100204354-A1 | COMPOSITIONS COMPRISING POLYPHOSPHONATES AND ADDITIVES THAT EXHIBIT AN ADVANTAGEOUS COMBINATION OF PROPERTIES, AND METHODS RELATED THERETO | FRX POLYMERS, INC. (US) | 2010-08-12 | — | — | US | disclosed |