SCHEMBL2801169

SCHEMBL2801169

CC(C)(C)c1cc(C(C)(CC(=O)O)c2ccc(O)c(C(C)(C)C)c2)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.48
FYN P06241 1/20 0.48
PDGFRB P09619 1/20 0.48
PIM1 P11309 1/20 0.48
FGFR1 P11362 1/20 0.48
FLT1 P17948 1/20 0.48
GRK5 P34947 1/20 0.48
MAP2K2 P36507 1/20 0.48
MAPK8 P45983 1/20 0.48
CDK8 P49336 1/20 0.48
RPS6KA3 P51812 1/20 0.48
PRKX P51817 1/20 0.48
JAK3 P52333 1/20 0.48
LIMK1 P53667 1/20 0.48
BTK Q06187 1/20 0.48
TYRO3 Q06418 1/20 0.48
MAPK14 Q16539 1/20 0.48
TAOK1 Q7L7X3 1/20 0.48
CAMK1D Q8IU85 1/20 0.48
AURKB Q96GD4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758423 1.00 CHEK1 (0.48) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL29357116 1.00 CHEK1 (0.48) CHEK1FYNPDGFRBPIM1FGFR1
Ethylene SCHEMBL6266470 0.97 CHEK1 (0.46) CHEK1FYNPDGFRBPIM1FGFR1
Ethylene Glycol SCHEMBL39427 0.95 CHEK1 (0.44) CHEK1FYNPDGFRBPIM1FGFR1
Glycolic Acid SCHEMBL5562280 0.95 CHEK1 (0.44) CHEK1FYNPDGFRBPIM1FGFR1
Ethylene Glycol SCHEMBL11709595 0.95 CHEK1 (0.44) CHEK1FYNPDGFRBPIM1FGFR1
1,4-Butanediol SCHEMBL11709268 0.93 CHEK1 (0.43) CHEK1FYNPDGFRBPIM1FGFR1
1,3-Propanediol SCHEMBL11708184 0.93 CHEK1 (0.43) CHEK1FYNPDGFRBPIM1FGFR1
1,6-Hexanediol SCHEMBL11706008 0.91 CHEK1 (0.42) CHEK1FYNPDGFRBPIM1FGFR1
SCHEMBL10028285 0.87 ALDH1A1 (0.47) CHEK1FYNPDGFRBPIM1FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055132-B1 PROCESS OF REDUCING MALODORS ON FABRICS PROCTER & GAMBLE (US) 2023-12-27 EP claimed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
US-20210139816-A1 PROCESS OF REDUCING MALODORS ON FABRICS THE PROCTER & GAMBLE COMPANY 2021-05-13 US claimed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US claimed
EP-2764410-B1 SHAPING OF AN INTEGRAL TRANSPARENT CLOCK COMPONENT ETA SA MFT HORLOGÈRE SUISSE (CH) 2017-08-30 EP claimed
US-9206299-B2 PVB film with UV protection and low yellow value for laminated safety glass KURARAY EUROPE GMBH (DE) 2015-12-08 US claimed
US-20140371356-A1 PVB Film With UV Protection and Low Yellow Value For Laminated Safety Glass KURARAY EUROPE GMBH (DE) 2014-12-18 US claimed
EP-0524640-B1 Diarylphosphinous acid arylesters, process for their preparation and their use to stabilize polymers, in particular polyolefin moulding compositions HOECHST AG (DE) 1997-01-29 EP claimed
US-5356967-A Raeacting formed Grignard reagent with a chloro-dibenzooxa-phosphorine derivative HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US claimed
EP-0472564-B1 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AG (DE) 1994-09-21 EP claimed
US-5298541-A Molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-29 US claimed
US-5281640-A For thermoplastic or thermosetting plastics, polymer-containing polymerized mono- or diolefin molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-25 US claimed
EP-0524640-A1 Diarylphosphinous acid arylesters, process for their preparation and their use to stabilize polymers, in particular polyolefin moulding compositions HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-27 EP claimed
EP-0489050-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-10 EP claimed
US-5109043-A Reacting 4,4'-dihalobiphenyl with suspension of finely divided magnesium to form grignard reagent HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-28 US claimed
EP-0374761-B1 PROCESS FOR THE PREPARATION OF ORGANOPHOSPHORUS COMPOUNDS OF 4,4-DIORGANOMAGNESIUM BIPHENYL, AND USE OF ORGANOPHOSPHORUS COMPOUNDS AS STABILIZERS FOR POLYMERS, PARTICULARLY POLYOLEFINE MOULDING COMPOSITIONS HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-05 EP claimed
WO-1991002738-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO claimed
WO-1990014349-A2 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO claimed
EP-0374761-A1 Process for the preparation of organophosphorus compounds of 4,4-diorganomagnesium biphenyl, and use of organophosphorus compounds as stabilizers for polymers, particularly polyolefine moulding compositions HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP claimed
EP-0324106-A1 Use of a polyolefin moulding composition for long term contact with an extracting medium HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP claimed