Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phomopsolide B SCHEMBL9474278 | 1.00 | XPO1 (0.34) | XPO1 | |
| Phomopsolide A SCHEMBL9477608 | 0.84 | XPO1 (0.39) | XPO1 | |
| Phomopsolide A SCHEMBL9475388 | 0.84 | XPO1 (0.39) | XPO1 | |
| Phomopsolide A SCHEMBL29378213 | 0.84 | XPO1 (0.39) | XPO1 | |
| SCHEMBL8420179 | 0.73 | XPO1 (0.35) | XPO1 | |
| SCHEMBL9475066 | 0.71 | — | — | |
| SCHEMBL29390553 | 0.64 | — | — | |
| SCHEMBL17350020 | 0.59 | CA12 (0.41) | XPO1 | |
| Asperlin SCHEMBL8418444 | 0.59 | CA12 (0.38) | XPO1 | |
| Asperlin SCHEMBL34463245 | 0.59 | CA12 (0.38) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-16 | — | — | US | disclosed |
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2010075282-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | UNIVERSITY OF WASHINGTON (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | WNT1, CTNNB1, WNT3A | XPO1 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.