Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4760758 | 0.98 | MAPT (0.51) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL15954597 | 0.98 | MAPT (0.51) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| Benzene SCHEMBL28299279 | 0.98 | KMT2A (0.51) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL1004433 | 0.95 | CYP3A4 (0.55) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL1004554 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL421013 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL1002777 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL1003944 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL1004461 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 | |
| SCHEMBL5566506 | 0.93 | LMNA (0.58) | MAPTCYP3A4KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221554-A | Method for preparing antibacterial agent 2, 2-dithio-bis (n-butylbenzamide) | 常州大学 | 2024-06-21 | — | — | CN | claimed |
| JP-2011524867-A | — | — | 2011-09-08 | — | — | JP | claimed |
| CN-102060857-A | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA SPA | 2011-05-18 | — | — | CN | claimed |
| EP-2300472-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2011-03-30 | — | — | EP | claimed |
| EP-2271646-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-01-12 | — | — | EP | claimed |
| WO-2009149139-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-10 | — | — | WO | claimed |
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | claimed |
| WO-2009077608-A1 | 2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS | PALAU PHARMA, S. A. (ES) | 2009-06-25 | — | — | WO | claimed |
| CN-101223141-A | Certain substituted amides, method of making, and method of use thereof | CGI PHARMACEUTICALS INC (US) | 2008-07-16 | — | — | CN | claimed |
| CN-101208306-A | Pyrazole compounds and diabetes therapeutic agent containing the same | JAPAN TOBACCO INC (JP) | 2008-06-25 | — | — | CN | claimed |
| CN-101115710-A | Diamine calcium channel blockers | NEUROMED PHARMACEUTICALS LTD (CA) | 2008-01-30 | — | — | CN | claimed |
| CN-100354276-C | Biologically active compounds | AMURA THERAPEUTICS LTD (GB) | 2007-12-12 | — | — | CN | claimed |
| CN-1993331-A | N- (1- (1-benzyl -4-phenyl-1h-imidazol-2-yl) -2,2-dymethylpropyl) benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer | CHIRON CORP (US) | 2007-07-04 | — | — | CN | claimed |
| CN-1681817-A | Biologically active compounds | AMURA THERAPEUTICS LTD (GB) | 2005-10-12 | — | — | CN | claimed |
| CN-1447810-A | Bicyclic pyrazoles with kinase inhibitor activity, process for their preparation and pharmaceutical compositions containing them | PHARMACIA ITALIA SPA (IT) | 2003-10-08 | — | — | CN | claimed |
| US-12415822-B2 | Small molecule inhibitors selective for polo-like kinase protein | UNIVERSITY OF SOUTH CAROLINA (US) | 2025-09-16 | — | — | US | disclosed |
| CN-118290448-A | Mixed amide zinc-oxygen alkane complex and preparation method and application thereof | 江苏爱姆欧光电材料有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-0323887-A2 | Heat-sensitive diazo recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |
| US-4792628-A | ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| US-3982931-A | N,N-di-sec.butyl-benzamide herbicides | MONTEDISON S.P.A. (IT) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12415822-B2 | Small molecule inhibitors selective for polo-like kinase protein | PLK2, PLK4, PLK3 | MAPT 1446/4885CYP3A4 4617/4885KMT2A 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.