Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584469 | 0.89 | ALDH1A1 (0.36) | ALDH1A1NPSR1CES2BCHEGAA | |
| SCHEMBL12584534 | 0.87 | OPRK1 (0.38) | ALDH1A1NPSR1CES2BCHEGAA | |
| SCHEMBL10028483 | 0.86 | ALDH1A1 (0.46) | ALDH1A1NPSR1CES2BCHEGAA | |
| SCHEMBL12584519 | 0.85 | ALDH1A1 (0.38) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL12584074 | 0.85 | NR1H3 (0.43) | ALDH1A1BCHEGAAKMT2AMEN1 | |
| SCHEMBL13705938 | 0.83 | ALDH1A1 (0.41) | ALDH1A1NPSR1CES2BCHEGAA | |
| SCHEMBL12584075 | 0.82 | HSP90AA1 (0.41) | ALDH1A1GAAKMT2AMAPTCYP1A2 | |
| SCHEMBL10062634 | 0.81 | ALDH1A1 (0.42) | ALDH1A1NPSR1CES2BCHEGAA | |
| SCHEMBL13705923 | 0.80 | TTR (0.41) | ALDH1A1CES1KMT2AMEN1MAPT | |
| SCHEMBL12584532 | 0.80 | ALDH1A1 (0.38) | ALDH1A1NPSR1CES2BCHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106203-B2 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| EP-2096110-B1 | Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase | LUMIGEN INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20090246819-A1 | Assay Methods Using Chemiluminescent Detection of Peroxidase | LUMIGEN, INC. | 2009-10-01 | — | — | US | disclosed |
| EP-2096110-A1 | Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7560556-B2 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| EP-1456176-B1 | IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN INC (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7247726-B2 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2007-07-24 | — | — | US | disclosed |