SCHEMBL1002902

SCHEMBL1002902

Cc1coc2c(C)c3oc(=O)ccc3cc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 9/20 0.55
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 4/20 0.52
TSHR P16473 3/20 0.52
MAPK1 P28482 3/20 0.50
CYP3A4 P08684 3/20 0.50
MAOA P21397 3/20 0.50
CYP1A2 P05177 2/20 0.50
HTR2C P28335 1/20 0.50
ADORA2A P29274 1/20 0.50
HSD17B10 Q99714 2/20 0.46
KMT2A Q03164 1/20 0.43
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
ACHE P22303 1/20 0.41
PDE4A P27815 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185977 0.78 KDM4E (0.68) KCNA3KDM4EALDH1A1TSHRMAPK1
SCHEMBL8416177 0.75 CYP3A4 (0.64) KCNA3KDM4EALDH1A1TSHRMAPK1
SCHEMBL10405129 0.73 ALDH1A1 (0.60) KDM4EALDH1A1TSHRMAPK1CYP3A4
SCHEMBL9120159 0.72 ALDH1A1 (0.63) KCNA3KDM4EALDH1A1TSHRCYP3A4
SCHEMBL31516460 0.72 ALDH1A1 (0.63) KCNA3KDM4EALDH1A1TSHRCYP3A4
SCHEMBL27987501 0.71 GAA (0.56) KDM4EALDH1A1MAPK1CYP3A4MAOA
SCHEMBL8750107 0.71 ALDH1A1 (0.48) KDM4EALDH1A1MAPK1CYP3A4MAOA
SCHEMBL6545566 0.71 KDM4E (0.62) KCNA3KDM4EALDH1A1TSHRMAPK1
SCHEMBL18073906 0.71 KCNA3 (0.76) KCNA3KDM4EALDH1A1TSHRCA9
SCHEMBL18073923 0.71 KCNA3 (1.00) KCNA3KDM4EALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579784-B1 METHOD FOR PREVENTING RESTENOSIS FOLLOWING RECONFIGURATION OF BODY VESSELS ADVANCED RES & TECH INST (US) 1999-11-10 EP claimed
US-5219882-A Treatment methods for lymes disease and associated debilitating conditions BISACCIA EMIL (US) 1993-06-15 US claimed
EP-0453497-A4 TREATMENT METHODS AND VACCINES 1992-10-07 EP claimed
US-5116864-A Method for preventing restenosis following reconfiguration of body vessels INDIANA UNIVERSITY FOUNDATION (US) 1992-05-26 US claimed
EP-0453497-A1 TREATMENT METHODS AND VACCINES BISACCIA, Emil (US) 1991-10-30 EP claimed
US-4960408-A ADMINISTERING A PSORALEN COMPOUND, EXPOSING TO ELECTROMAGNETIC RADIATION KLAINER ALBERT S (US) 1990-10-02 US claimed
WO-1990007952-A1 TREATMENT METHODS AND VACCINES BISACCIA EMIL (US) 1990-07-26 WO claimed
US-4748120-A Photochemical decontamination treatment of whole blood or blood components DIAMOND SCIENTIFIC CO. (US) 1988-05-31 US claimed
WO-2023164075-A1 THERMOSTABLE UV INACTIVATED VACCINES AND OTHER BIOPHARMACEUTICALS UNIVERSAL STABILIZATION TECHNOLOGIES INC. (US) 2023-08-31 WO disclosed
US-20220168411-A1 PSORALEN-INACTIVATED CORONAVIRUS VACCINE AND METHOD OF PREPARATION THE UNITED STATES OF AMERICAN AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-06-02 US disclosed
US-20150291936-A1 PSORALEN-INACTIVATED DENGUE VIRUS VACCINE AND METHOD OF PREPARATION THE UNITED STATES OF AMERICAN AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-10-15 US disclosed
US-9005633-B2 Psoralen-inactivated viral vaccine and method of preparation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY. (US) 2015-04-14 US disclosed
US-20110014233-A1 PSORALEN-INACTIVATED VIRAL VACCINE AND METHOD OF PREPARATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2011-01-20 US disclosed
WO-2004101805-A1 METHOD FOR RECOMBINANT PRODUCTION OF MAMMALIAN PROTEINS AND PROTEINS OBTAINABLE BY SUCH METHOD AXXIMA PHARMACEUTICALS AG (DE) 2004-11-25 WO disclosed
US-4545987-A Psoralen inactivated double-stranded RNA viral vaccines ADVANCED GENETICS RESEARCH INSTITUTE (US) 1985-10-08 US disclosed
EP-0030358-B1 APPARATUS FOR REDUCING THE FUNCTIONING LYMPHOCYTE POPULATION IN BLOOD LEUKOCYTE RESEARCH, INC. (US) 1985-03-27 EP disclosed
EP-0124363-A2 Photochemical decontamination treatment of whole blood or blood components DIAMOND SCIENTIFIC CO. (US) 1984-11-07 EP disclosed
US-4321919-A Method and system for externally treating human blood LEUKOCYTE RESEARCH, INC. (US) 1982-03-30 US disclosed
US-4279922-A Photosensitizing benzofuranacrylics THOMAS C. ELDER, INC. (US) 1981-07-21 US disclosed
EP-0030358-A2 Apparatus for reducing the functioning lymphocyte population in blood LEUKOCYTE RESEARCH, INC. (US) 1981-06-17 EP disclosed