Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635908 | 0.84 | CFTR (0.56) | CFTRGOPCCHRM2CHRM4GAA | |
| SCHEMBL9304904 | 0.81 | CFTR (0.54) | CFTRGOPCCHRM2CHRM4GAA | |
| SCHEMBL21922362 | 0.71 | CHRM2 (0.45) | CFTRGOPCCHRM2CHRM4GAA | |
| SCHEMBL4567643 | 0.68 | HCAR2 (0.39) | LMNAMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL3886398 | 0.68 | CFTR (1.00) | CFTRGOPCGAAPKMHSP90AA1 | |
| SCHEMBL11469864 | 0.67 | CFTR (0.39) | CFTRGOPCCHRM2CHRM4GAA | |
| SCHEMBL10029373 | 0.65 | ELANE (0.36) | CFTRGOPCCHRM2LMNAALDH1A1 | |
| SCHEMBL28548234 | 0.65 | HCAR2 (0.53) | CFTRGOPCCHRM2CHRM4SMN1; SMN2 | |
| SCHEMBL12249757 | 0.65 | CFTR (0.42) | CFTRGOPCCHRM2CHRM4GAA | |
| SCHEMBL11263455 | 0.65 | PTGER3 (0.50) | CFTRGOPCCHRM2CHRM4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2012-01-26 | — | — | US | disclosed |
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2012-01-26 | — | — | US | disclosed |
| WO-2010103405-A2 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | CHRM1, OPRM1, CHRM2 | CFTR 4639/4885GOPC 3496/4885CHRM2 3/4885 |
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | CFH, C5, CHRM1 | CFTR 4702/4885GOPC 2362/4885CHRM2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.