Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593804 | 0.71 | CFTR (0.56) | TSHRLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10029374 | 0.68 | CFTR (0.52) | HCAR2TSHRLMNAHSD17B10MEN1 | |
| SCHEMBL12315433 | 0.63 | CHRM2 (0.40) | HCAR2TSHRLMNAMEN1KMT2A | |
| SCHEMBL11001594 | 0.62 | CFTR (0.41) | HCAR2TSHRLMNAHSD17B10LDHA | |
| SCHEMBL754463 | 0.60 | SLC6A3 (0.41) | HCAR2LMNASLC6A2MEN1KMT2A | |
| SCHEMBL5340915 | 0.59 | CHRM2 (0.35) | HCAR2TSHRLMNASLC6A2MEN1 | |
| SCHEMBL5340920 | 0.59 | CHRM2 (0.35) | HCAR2TSHRLMNASLC6A2MEN1 | |
| SCHEMBL5848595 | 0.57 | HCAR2 (0.36) | HCAR2TSHRLMNAHSD17B10SLC6A2 | |
| SCHEMBL1309560 | 0.56 | OPRM1 (0.54) | TSHRLMNASLC6A2MEN1KMT2A | |
| SCHEMBL1310931 | 0.56 | OPRM1 (0.54) | TSHRLMNASLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680297-B2 | Manufacturing process for tiotropium bromide | Drug Process Licensing Assoc., LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680297-B2 | Manufacturing process for tiotropium bromide | Drug Process Licensing Assoc., LLC (US) | 2014-03-25 | — | — | US | disclosed |
| WO-2013050929-A1 | MANUFACTURING PROCESS FOR TIOTROPIUM BROMIDE | DRUG PROCESS LICENSING ASS., LLC (US) | 2013-04-11 | — | — | WO | disclosed |
| US-20120123125-A1 | Manufacturing process for tiotropium bromide | Drug Process Licensing Associates, LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120123125-A1 | Manufacturing process for tiotropium bromide | Drug Process Licensing Associates, LLC (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123125-A1 | Manufacturing process for tiotropium bromide | CA5B, CA7, CHRM3 | HCAR2 107/4885TSHR 1193/4885LMNA 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.