Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641570 | 0.81 | ALDH1A1 (0.34) | ALDH1A1TDP1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9247739 | 0.81 | POLB (0.40) | MAP3K14ALDH1A1KMT2ACRBNDDB1 | |
| SCHEMBL13007383 | 0.81 | MAP3K14 (0.38) | MAP3K14ALDH1A1CRBNDDB1SMN1; SMN2 | |
| SCHEMBL6598019 | 0.78 | NPC1 (0.42) | MAP3K14ALDH1A1KMT2ACRBNDDB1 | |
| SCHEMBL24180058 | 0.78 | MAP3K14 (0.35) | MAP3K14TDP1CRBNDDB1SMN1; SMN2 | |
| SCHEMBL22746549 | 0.77 | DDB1 (0.36) | MAP3K14CRBNDDB1SMN1; SMN2 | |
| SCHEMBL18888757 | 0.77 | NPC1 (0.41) | MAP3K14ALDH1A1KMT2ACRBNDDB1 | |
| SCHEMBL15606251 | 0.76 | MAP3K14 (0.40) | MAP3K14CRBNDDB1SMN1; SMN2NPC1 | |
| SCHEMBL20801365 | 0.76 | SMN1; SMN2 (0.38) | MAP3K14ALDH1A1TDP1KMT2ACRBN | |
| SCHEMBL24756756 | 0.75 | ALDH1A1 (0.42) | MAP3K14ALDH1A1KMT2ACRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9119874-B2 | Cell-penetrating markers of apoptosis | TRUSTEES OF BOSTON COLLEGE (US) | 2015-09-01 | — | — | US | disclosed |
| US-20120021933-A1 | SMALL MOLECULE PRINTING | PARK SEUNG BUM (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120021933-A1 | SMALL MOLECULE PRINTING | PARK SEUNG BUM (US) | 2012-01-26 | — | — | US | disclosed |
| US-7932213-B2 | Solid phase synthesis with benzylidene linker attaching compound on glass slide; microarrays; drug screening | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-04-26 | — | — | US | disclosed |
| US-7932213-B2 | Solid phase synthesis with benzylidene linker attaching compound on glass slide; microarrays; drug screening | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-04-26 | — | — | US | disclosed |