Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 13/20 | 0.68 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.65 |
| ▸ | REN | P00797 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029543 | 0.90 | CTSD (0.57) | CTSDPSMB5REN | |
| SCHEMBL10029542 | 0.90 | REN (0.59) | CTSDPSMB5REN | |
| SCHEMBL10029541 | 0.89 | CTSD (0.56) | CTSDPSMB5REN | |
| SCHEMBL10029538 | 0.89 | CTSD (0.56) | CTSDPSMB5REN | |
| SCHEMBL10029544 | 0.87 | CTSD (0.59) | CTSDPSMB5REN | |
| SCHEMBL8479400 | 0.87 | REN (0.73) | CTSDREN | |
| SCHEMBL10029533 | 0.85 | CTSD (0.53) | CTSDPSMB5REN | |
| SCHEMBL17770758 | 0.85 | CTSD (0.68) | CTSDPSMB5REN | |
| SCHEMBL17969276 | 0.84 | CTSD (0.85) | CTSD | |
| SCHEMBL17969275 | 0.84 | CTSD (0.85) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809498-B2 | Pepstatin A derivatives | FREIE UNIVERSITAET BERLIN (DE) | 2014-08-19 | — | — | US | disclosed |
| US-20120016103-A1 | PEPSTATIN A DERIVATIVES | FREIE UNIVERSITAET BERLIN | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016103-A1 | PEPSTATIN A DERIVATIVES | PEPD, ANPEP, VIP | CTSD 845/4885PSMB5 782/4885REN 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.