SCHEMBL10029668

SCHEMBL10029668

FC(F)(F)c1cc(C(F)(F)F)c(C(=S)c2c(C(F)(F)F)cc(C(F)(F)F)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
GAA P10253 2/20 0.35
AKT1 P31749 1/20 0.34
CACNA1H O95180 1/20 0.33
CACNA1B Q00975 1/20 0.33
CACNA1C Q13936 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
AR P10275 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA2 P00918 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NOTUM Q6P988 1/20 0.32
GPR35 Q9HC97 1/20 0.31
GPR17 Q13304 1/20 0.31
MYC P01106 1/20 0.31
MAX P61244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20560211 0.82 CES2 (0.38) CES2GAAAKT1CACNA1HCACNA1B
SCHEMBL4088507 0.80 CES2 (0.43) CES2CACNA1HCACNA1BCACNA1CAR
SCHEMBL18378522 0.76 CES2 (0.41) CES2CACNA1HCACNA1BCACNA1CMAPT
SCHEMBL3369693 0.74 CES2 (0.48) CES2ALDH1A1KDM4ENOTUMGPR35
SCHEMBL30628783 0.73 CES2 (0.47) CES2CACNA1HMAPTNPSR1NOTUM
SCHEMBL18394005 0.73 CES2 (0.47) CES2MAPTNOTUMGPR35GPR17
SCHEMBL31031802 0.73 CES2 (0.43) CES2MAPTNOTUMGPR35GPR17
SCHEMBL31031798 0.73 CES2 (0.43) CES2MAPTNOTUMGPR35GPR17
SCHEMBL29592486 0.72 CES2 (0.40) CES2GAACACNA1HCACNA1BCACNA1C
SCHEMBL391593 0.72 CES2 (0.45) CES2CACNA1HCACNA1BCACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed