SCHEMBL10029705

SCHEMBL10029705

O=C(c1cccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1)c1cccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
SRD5A2 P31213 2/20 0.56
ALDH1A1 P00352 2/20 0.52
PBRM1 Q86U86 1/20 0.52
CES2 O00748 1/20 0.47
ACHE P22303 3/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.44
PTGS1 P23219 2/20 0.44
PTGS2 P35354 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
VNN1 O95497 1/20 0.44
CXCR1 P25024 1/20 0.44
CXCR2 P25025 1/20 0.44
RECQL P46063 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684740 0.84 ATM (0.63) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL27811835 0.84 ALDH1A1 (0.44) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL30389182 0.82 ATM (0.65) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL11395047 0.80 ALDH1A1 (0.67) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL1044812 0.80 SRD5A2 (0.83) ATMTDP1L3MBTL1SRD5A2CES2
SCHEMBL548283 0.79 L3MBTL1 (0.61) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL7488968 0.77 ATM (0.59) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL30238332 0.77 L3MBTL1 (0.59) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL135162 0.77 ATM (1.00) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL9324919 0.77 ATM (1.00) ATMTDP1L3MBTL1SRD5A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed