SCHEMBL10029905

SCHEMBL10029905

CC1(C)c2cc(N(c3ccccc3)c3ccc4c(c3)C(C)(C)c3cc(-n5c6ccccc6c6ccccc65)ccc3-4)ccc2-c2ccc(-n3c4ccccc4c4ccccc43)cc21

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDK2 Q15119 1/20 0.32
ALK Q9UM73 2/20 0.31
APP P05067 1/20 0.31
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15138063 1.00 KDM4E (0.39) KDM4EATML3MBTL1PDK2ALK
SCHEMBL9921628 1.00 KDM4E (0.39) KDM4EATML3MBTL1PDK2ALK
SCHEMBL10029885 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2
SCHEMBL1593388 0.96 KDM4E (0.44) KDM4EATML3MBTL1PDK2ALK
SCHEMBL13518235 0.96 KDM4E (0.44) KDM4EATML3MBTL1PDK2ALK
SCHEMBL29373577 0.96 KDM4E (0.44) KDM4EATML3MBTL1PDK2ALK
SCHEMBL15138327 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL12367634 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2APP
SCHEMBL9881116 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL12367422 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877464-B2 Organic light emitting element LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11877464-B2 Organic light emitting element LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-11575087-B1 Organic electroluminescence device, light emitting device, organic electroluminescence display device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-02-07 US disclosed
US-20230036664-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, LIGHT EMITTING DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 US disclosed
US-20210328156-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-21 US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20110024736-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY SONY CORPORATION (JP) 2011-02-03 US disclosed
US-20110024736-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY SONY CORPORATION (JP) 2011-02-03 US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 US disclosed
US-20100252823-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20100252823-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 KDM4E 1889/4885ATM 3641/4885L3MBTL1 1564/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 KDM4E 502/4885ATM 1740/4885L3MBTL1 204/4885
US-11877464-B2 Organic light emitting element CACNA2D4, CYBA, L1CAM KDM4E 3566/4885ATM 2446/4885L3MBTL1 686/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 KDM4E 2498/4885ATM 3497/4885L3MBTL1 2530/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 KDM4E 502/4885ATM 1740/4885L3MBTL1 204/4885
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SCO2, NUDC KDM4E 1692/4885ATM 2682/4885L3MBTL1 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.