SCHEMBL10030615

SCHEMBL10030615

CC(C)(C)OC(=O)NCCCC(N)(CCCNC(=O)OC(C)(C)C)CCCNC(=O)OC(C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
MEN1 O00255 1/20 0.57
GAA P10253 1/20 0.57
KMT2A Q03164 1/20 0.57
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
CA1 P00915 11/20 0.50
CA2 P00918 11/20 0.50
CA12 O43570 7/20 0.50
CA9 Q16790 7/20 0.50
EPHX1 P07099 1/20 0.43
HTT P42858 1/20 0.42
STK17B O94768 1/20 0.42
STK17A Q9UEE5 1/20 0.42
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557954 0.95 TDP1 (0.56) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7097924 0.95 TDP1 (0.65) TDP1MEN1GAAKMT2AMAOA
SCHEMBL16358704 0.92 TDP1 (0.53) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7095175 0.91 TDP1 (0.55) TDP1MEN1GAAKMT2AMAOA
SCHEMBL7096665 0.91 TDP1 (0.55) TDP1MEN1GAAKMT2AMAOA
SCHEMBL30980540 0.89 TDP1 (0.61) TDP1MEN1GAAKMT2AMAOA
SCHEMBL14738985 0.89 TDP1 (0.61) TDP1MEN1GAAKMT2AMAOA
SCHEMBL15612944 0.89 TDP1 (0.55) TDP1MEN1GAAKMT2AMAOA
SCHEMBL21320306 0.87 TDP1 (0.59) TDP1MEN1GAAKMT2AMAOA
SCHEMBL19591067 0.86 CA12 (0.58) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2025035040-A1 LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES LYCIA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
US-20210003506-A1 FLUORESCENCE SPECTRAL SHAPE ANALYSIS FOR ANALYTE RECOGNITION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-01-07 US disclosed
WO-2016192528-A1 Trimaleimide Linkers and Uses Thereof NEWBIO THERAPEUTICS, INC. (CN) 2016-12-08 WO disclosed
US-9302012-B2 Anti-bacterial siderophore-aminopenicillin conjugates UNIVERSITY OF NOTRE DAME DU LAC (US) 2016-04-05 US disclosed
US-20130281424-A1 ANTI-BACTERIAL SIDEROPHORE-AMINOPENICILLIN CONJUGATES UNIVERSITY OF NOTRE DAME DU LAC (US) 2013-10-24 US disclosed
US-8475768-B2 Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) GE HEALTHCARE AS (NO) 2013-07-02 US disclosed
US-8158804-B2 Chelating agents GE HEALTHCARE AS (NO) 2012-04-17 US disclosed
US-8158804-B2 Chelating agents GE HEALTHCARE AS (NO) 2012-04-17 US disclosed
US-20100056787-A1 CHELATING AGENTS GE HEALTHCARE AS (NO) 2010-03-04 US disclosed
US-20100056787-A1 CHELATING AGENTS GE HEALTHCARE AS (NO) 2010-03-04 US disclosed
WO-2008085064-A2 HYDROXYPYRIDINONE CHELATING AGENTS, THEIR METAL COMPLEXES AND THEIR USE AS MRI CONTRAST AGENTS GE HEALTHCARE AS (NO) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281424-A1 ANTI-BACTERIAL SIDEROPHORE-AMINOPENICILLIN CONJUGATES SLC7A1, SLC7A5, SLC40A1 TDP1 4294/4885MEN1 4667/4885GAA 395/4885
US-20100056787-A1 CHELATING AGENTS SLC39A3, SLC40A1, TFRC TDP1 3059/4885MEN1 249/4885GAA 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.