SCHEMBL10030765

SCHEMBL10030765

CCC1(COC(=O)C(=O)OC)COC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CTSK P43235 4/20 0.37
POLB P06746 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30775580 0.85 ALDH1A1 (0.46) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL28031397 0.85 TSHR (0.43) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL17451609 0.84 TSHR (0.44) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL17383697 0.82 TSHR (0.43) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL12263773 0.81 TSHR (0.48) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL1813100 0.81 TSHR (0.47) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL13374666 0.81 TSHR (0.42) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL156498 0.81 ALDH1A1 (0.42) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL3462874 0.79 TSHR (0.46) TSHRMEN1KMT2ACTSKPOLB
SCHEMBL1813102 0.79 TSHR (0.46) TSHRMEN1KMT2ACTSKPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-8704348-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2014-04-22 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-20140061905-A1 Polyol Photosensitizers, Carrier Gas UV Laser Ablation Sensitizers, and Other Additives and Methods For Making and Using Same NDSU RESEARCH FOUNDATION (US) 2014-03-06 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-8445174-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2013-05-21 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-20120196948-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2012-08-02 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-8114567-B2 Polyol photosensitizers, carrier gas UV laser ablation sensitizers, and other additives and methods for making and using same NDSU RESEARCH FOUNDATION (US) 2012-02-14 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION 2009-07-23 US disclosed
WO-2007124073-A2 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME NDSU RESEARCH FOUNDATION (US) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184417-A1 POLYOL PHOTOSENSITIZERS, CARRIER GAS UV LASER ABLATION SENSITIZERS, AND OTHER ADDITIVES AND METHODS FOR MAKING AND USING SAME OTC, ODC1, OXGR1 TSHR 3984/4885MEN1 4576/4885KMT2A 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.