Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 5/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031313 | 0.86 | SLC5A1 (0.54) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL10031311 | 0.79 | SLC5A1 (0.48) | SLC5A1SLC5A2CNR2P2RX3MAPT | |
| SCHEMBL10064922 | 0.78 | SLC5A1 (0.57) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL10031310 | 0.77 | SLC5A1 (0.56) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL10031323 | 0.74 | SLC5A1 (0.54) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL16845135 | 0.72 | SLC5A1 (0.56) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL19114941 | 0.70 | SLC5A1 (0.51) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL3841654 | 0.68 | ENPP1 (0.53) | MAPTALDH1A1ENPP1LMNA | |
| SCHEMBL23436552 | 0.68 | SLC5A1 (0.54) | SLC5A1SLC5A2P2RX3MAPTALDH1A1 | |
| SCHEMBL14862842 | 0.68 | SLC5A2 (0.80) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053330-A1 | Chemical Process | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053330-A1 | Chemical Process | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
| WO-2010127067-A1 | CHEMICAL PROCESS | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053330-A1 | Chemical Process | SLC5A2, SLC5A1, UGGT1 | SLC5A1 2/4885SLC5A2 1/4885CNR2 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.