Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506733 | 0.85 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL10064478 | 0.83 | SMN1; SMN2 (0.57) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL10064481 | 0.83 | SMN1; SMN2 (0.61) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL21770322 | 0.79 | HPGD (0.55) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL10031402 | 0.76 | SMN1; SMN2 (0.65) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL20826393 | 0.76 | MAPT (0.64) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL12395553 | 0.76 | MAPT (0.64) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL30627676 | 0.76 | MAPT (0.57) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL18647502 | 0.75 | IDO1 (0.51) | KDM4ENPC1TSHRADRB2ADRB1 | |
| SCHEMBL10064480 | 0.74 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460636-B2 | Complex compound and MRI probe made of same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8460636-B2 | Complex compound and MRI probe made of same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20120093735-A1 | COMPLEX COMPOUND AND MRI PROBE MADE OF SAME | SUZUKI KOJI (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120093735-A1 | COMPLEX COMPOUND AND MRI PROBE MADE OF SAME | SUZUKI KOJI (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20110165089-A1 | Complex Compound and MRI Probe Made of Same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093735-A1 | COMPLEX COMPOUND AND MRI PROBE MADE OF SAME | KCNN2, KCNN1, KCNN3 | KDM4E 2786/4885SMN1; SMN2 2353/4885LMNA 4394/4885 |
| US-20110165089-A1 | Complex Compound and MRI Probe Made of Same | KCNN2, KCNN1, KCNN3 | KDM4E 2786/4885SMN1; SMN2 2353/4885LMNA 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.