Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.53 |
| ▸ | WNT3A | P56704 | 7/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114817 | 0.93 | ALDH1A1 (0.55) | HPGDCTNNB1WNT3AALDH1A1SMN1; SMN2 | |
| SCHEMBL21770378 | 0.88 | CTNNB1 (0.44) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL21753281 | 0.81 | PKM (0.65) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL10031397 | 0.79 | KDM4E (0.55) | HPGDTSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL24606355 | 0.78 | ALDH1A1 (0.52) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL29533755 | 0.78 | ALDH1A1 (0.52) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL30627676 | 0.78 | MAPT (0.57) | HPGDTSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8242151 | 0.77 | CTNNB1 (0.52) | CTNNB1WNT3ATSHRALDH1A1MAPT | |
| SCHEMBL16404991 | 0.77 | CTNNB1 (0.56) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL4085154 | 0.76 | MGLL (0.48) | TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2021-07-15 | — | — | US | disclosed |
| WO-2020039027-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | HPGD 1673/4885CTNNB1 3935/4885WNT3A 2322/4885 |
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | PREP, GAA, DNPEP | HPGD 1675/4885CTNNB1 3587/4885WNT3A 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.