Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.83 |
| ▸ | POLB | P06746 | 4/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.73 |
| ▸ | KIT | P10721 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.73 |
| ▸ | RELA | Q04206 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salvigenin SCHEMBL1427018 | 0.91 | FLT3 (1.00) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL28040107 | 0.91 | POLB (1.00) | FLT3MAPTPOLBKDM4EMEN1 | |
| Ladanein SCHEMBL737069 | 0.91 | FLT3 (0.81) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL28732976 | 0.90 | FLT3 (0.81) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL29504103 | 0.90 | FLT3 (0.81) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL15277726 | 0.89 | FLT3 (0.74) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL16525547 | 0.88 | POLB (0.73) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL30606765 | 0.88 | KDM4E (0.81) | FLT3MAPTPOLBKDM4EMEN1 | |
| SCHEMBL28660389 | 0.88 | KDM4E (0.81) | FLT3MAPTPOLBKDM4EMEN1 | |
| Tetramethylscutellarein SCHEMBL739115 | 0.88 | MEN1 (1.00) | FLT3MAPTPOLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828248-B1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |
| EP-2828248-B1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |
| US-20150056166-A1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150056166-A1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150056166-A1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| EP-2828248-A1 | FLAVONE DERIVATIVES AND THEIR USE | Twincore GmbH (DE) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013139487-A1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013139487-A1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013021258-A1 | ANTI-TUBERCULAR COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-02-14 | — | — | WO | disclosed |
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150056166-A1 | FLAVONE DERIVATIVES AND THEIR USE | MAVS, ZC3HAV1, EBNA1BP2 | FLT3 2216/4885MAPT 1594/4885POLB 1893/4885 |
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | HTR2C, GRIN2C, HTR5A | FLT3 3391/4885MAPT 1117/4885POLB 3613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.