SCHEMBL10032079

SCHEMBL10032079

COc1ccc(C(C)(C)c2cccc(C(C)(C)c3ccc(OC(C)=O)cc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
CYP3A4 P08684 1/20 0.46
BACE1 P56817 3/20 0.46
LMNA P02545 7/20 0.43
KMT2A Q03164 2/20 0.43
ELANE P08246 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTT P42858 2/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
ALDH1A1 P00352 5/20 0.41
F2 P00734 1/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10624763 0.94 ESR1 (0.55) ESR1ESR2CYP3A4LMNAKMT2A
SCHEMBL800223 0.91 LMNA (0.52) BACE1LMNAKMT2AELANEGAA
SCHEMBL13712362 0.91 LMNA (0.52) BACE1LMNAKMT2AELANEGAA
SCHEMBL14287528 0.89 ESR1 (0.50) ESR1ESR2CYP3A4LMNAKMT2A
SCHEMBL13526085 0.88 CYP3A4 (0.57) ESR1ESR2CYP3A4LMNAKMT2A
SCHEMBL11299180 0.87 CYP3A4 (0.50) CYP3A4BACE1LMNAKMT2AGAA
SCHEMBL14276111 0.87 CYP3A4 (0.50) CYP3A4BACE1LMNAKMT2AGAA
SCHEMBL12603929 0.86 LMNA (0.47) BACE1LMNAKMT2AELANEGAA
SCHEMBL16488964 0.86 HSD17B10 (0.53) ESR2CYP3A4BACE1LMNAKMT2A
SCHEMBL10112754 0.85 ESR1 (0.59) ESR1ESR2CYP3A4LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8795824-B2 Light diffusing resin composition and light diffusing plate using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-08-05 US disclosed
US-8119228-B2 Polycarbonate resin composition, optical molded body using the same, and illumination unit IDEMITSU KOSAN CO., LTD. (JP) 2012-02-21 US disclosed
US-7820778-B2 Light guide member and illumination unit IDEMITSU KOSAN CO., LTD. (JP) 2010-10-26 US disclosed
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20090186208-A1 LIGHT DIFFUSING RESIN COMPOSITION AND LIGHT DIFFUSING PLATE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-07-23 US disclosed
US-20090185363-A1 POLYCARBONATE RESIN COMPOSITION, OPTICAL MOLDED BODY USING THE SAME, AND ILLUMINATION UNIT IDEMITSU KOSAN CO., LTD. (JP) 2009-07-23 US disclosed
US-20090175052-A1 LIGHT GUIDE MEMBER AND ILLUMINATION UNIT IDEMITSU KOSAN CO., LTD (JP) 2009-07-09 US disclosed
US-20080146759-A1 Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material IDEMITSU KOSAN CO., LTD (JP) 2008-06-19 US disclosed
US-7317067-B2 Polycarbonate copolymer, and heat resistant parts comprising the same TEIJIN CHEMICALS (JP) 2008-01-08 US disclosed
US-7223451-B2 Polycarbonate-based oriented film and retardation film TEIJIN LIMITED (JP) 2007-05-29 US disclosed