SCHEMBL800223

SCHEMBL800223

COc1ccc(C(C)(C)c2ccc(OC(C)=O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
MAPT P10636 4/20 0.49
BACE1 P56817 2/20 0.49
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
APEX1 P27695 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
ELANE P08246 1/20 0.46
F2 P00734 1/20 0.44
GLA P06280 1/20 0.44
HPGD P15428 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13712362 1.00 LMNA (0.52) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL12603929 0.95 LMNA (0.47) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL16488964 0.95 HSD17B10 (0.53) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL10629411 0.92 LMNA (0.59) LMNAMAPTALDH1A1HSD17B10TDP1
SCHEMBL5491320 0.92 LMNA (0.59) LMNAMAPTALDH1A1HSD17B10TDP1
SCHEMBL16093179 0.91 KMT2A (0.53) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL13986166 0.91 BACE1 (0.49) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL10032079 0.91 ESR1 (0.49) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL15417137 0.91 BACE1 (0.49) LMNAMAPTBACE1ALDH1A1HSD17B10
SCHEMBL14682218 0.91 BACE1 (0.49) LMNAMAPTBACE1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239962-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO.,LTD. (JP) 2024-07-18 US disclosed
US-20240240370-A1 SYSTEMS AND METHODS FOR CONTINUOUS FABRICATION OF WOVEN COMPOSITE MATERIALS WEAV3D, Inc. 2024-07-18 US disclosed
US-20240240370-A1 SYSTEMS AND METHODS FOR CONTINUOUS FABRICATION OF WOVEN COMPOSITE MATERIALS WEAV3D, Inc. 2024-07-18 US disclosed
US-20240239962-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO.,LTD. (JP) 2024-07-18 US disclosed
US-20240218117-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES Visolis, Inc. 2024-07-04 US disclosed
US-20240067594-A1 METHODS OF PLASTIC RECYCLING USING HIGHLY EFFICIENT ORGANOCATALYSTS U. S. DEPARTMENT OF ENERGY 2024-02-29 US disclosed
WO-2024044568-A1 ANTIMICROBIAL POLYCARBONATE COATINGS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-02-29 WO disclosed
EP-3798263-B1 LOW TEMPERATURE FOAMABLE POLYCARBONATE COMPOSITION AND ARTICLES THEREOF SHPP GLOBAL TECH BV (NL) 2024-01-24 EP disclosed
US-20240018301-A1 POLYCARBONATE COPOLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-20240018301-A1 POLYCARBONATE COPOLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-7183342-B2 Flame-retardant aromatic polycarbonate resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-02-27 US disclosed
US-20070040963-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
US-20070027268-A1 Reaction product obtained by melt blending two aromatic polyester-polycarbonates and a transesterification catalyst that has a haze of less than 1.0% GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-20070026334-A1 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2007-02-01 US disclosed
US-7169887-B2 Thermoplastic molding material and moulded bodies produced therefrom TICONA GMBH (DE) 2007-01-30 US disclosed
US-20070019984-A1 Organic photoconductor, process cartridge and image forming apparatus both employing the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-25 US disclosed
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-7160659-B2 Electrophotographic apparatus and process cartridge CANON KABUSHIKI KAISHA (JP) 2007-01-09 US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 US disclosed
US-20070003848-A1 Image forming method, a processing cartridge and an image forming method using the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067594-A1 METHODS OF PLASTIC RECYCLING USING HIGHLY EFFICIENT ORGANOCATALYSTS PARG, PNISR, PARN LMNA 2593/4885MAPT 1763/4885BACE1 4832/4885
US-20240218117-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES COASY, FASN, GGPS1 LMNA 220/4885MAPT 2722/4885BACE1 2396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.