SCHEMBL10032191

SCHEMBL10032191

Cc1cccc(-c2ccc(-c3cccc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5ccccc45)c3)cn2)n1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
CCR1 P32246 1/20 0.39
CCR8 P51685 1/20 0.39
TGFBR1 P36897 3/20 0.37
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
CYP2A6 P11509 1/20 0.37
IKBKB O14920 1/20 0.36
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
METAP2 P50579 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032619 0.93 CCR1 (0.39) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032185 0.88 CYP11B2 (0.42) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032424 0.87 CYP2A6 (0.42) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032217 0.86 CYP11B2 (0.44) CYP17A1CYP19A1CYP11B1CYP11B2HSD17B1
SCHEMBL13016369 0.86 CYP11B1 (0.47) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032484 0.86 CYP2A6 (0.41) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032497 0.86 CCR1 (0.44) CCR1CCR8TGFBR1HSD17B1HSD17B2
SCHEMBL10032871 0.86 CCR1 (0.43) CCR1CCR8TGFBR1HSD17B1HSD17B2
SCHEMBL10032750 0.85 CYP2A6 (0.40) CYP17A1CYP19A1CYP11B1CYP11B2CCR1
SCHEMBL10032188 0.84 CYP11B2 (0.50) CYP17A1CYP19A1CYP11B1CYP11B2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed